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Job: Manager, Operations, Merck & Co., Durham, NC

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General Information

Job title:
Manager, Operations
Job location:
Durham, NC  27701 United States
Requisition code:
Date posted:
Job category:
Employment type:
Full time

Job Description

Job Description

Subject to applicable law, all prospective hires will be required to demonstrate that they have been fully vaccinated for COVID-19 or intend to be vaccinated for COVID-19 by November 1, 2021, or qualify for a medical or religious accommodation to this vaccination requirement. Hired candidates who are not vaccinated by November 1, 2021, and who have not been approved for a legally-required medical or religious accommodation will be subject to disciplinary action up to and including termination of employment, in accordance with applicable law.

Our Manufacturing Operations teams are the people that make our products. We work in the manufacturing plants with a "Safety First, Quality Always" mindset striving for continuous improvement. We work in the local plant connected to our global manufacturing network to ensure the highest quality of raw materials, intermediates and finished products.

Our Manufacturing Site in Durham, NC is hiring Operations Managers across multiple products and processes. The hiring team will determine based on your experience and skill set where you would make the greatest positive impact as an Operations Manager. These positions are day shift roles, typically with a 12 hour (6 am to 6 pm), rotating (2-2-3) schedule.

The role of Operations Manager at our Durham facility is a manufacturing first level management role.  The Operations Manager will provide direction, coaching, and technical expertise to operations personnel who are accountable for the manufacturing processes. They will also actively manage their assigned team to reliably support customer demand. This may include hiring as needed, employee development, coaching, and performance management.

Additionally, this role provides the opportunity to become proficient in the use of manufacturing systems and build knowledge of site procedures in order to resolve process/equipment issues, minimize downtime, and ensure product quality.

The Operations Manager leads the manufacturing process with a team assigned to vaccine or biologics manufacturing, as well as other production-related activities. This role as a Manager, Operations will be an energetic, leader with strong interpersonal, leadership, and collaboration skills responsible for supporting Operational Readiness projects to support biological processes for a new manufacturing facility or currently established manufacturing facility.

Position Responsibilities
Employee Development | People Management

  • Develop, motivate, and manage a team to ensure reliable manufacturing process execution

  • Assign yearly performance objectives for the team in alignment with department and site goals

  • Provide regular feedback and coaching to employees on work performance

  • Provide leadership to the team as needed based on the team's capabilities and maturity

  • Build team culture and mediate conflict as needed

Process Execution | Continuous Improvement

  • Provide a leadership presence on the manufacturing floor

  • Champion standard work to drive consistent use of best practices across teams

  • Assist the team in troubleshooting issues to minimize downtime and maintain product quality

  • Identify opportunities to improve the process (e.g. cycle times, ease of execution, reliability)

  • Support work as needed to implement improvements (e.g. scheduling, staffing, protocol execution)

  • Coach team members in executing smaller improvement projects in their operational area

  • Represent Operations on project teams as needed

  • Support operations production through start-up and commissioning and qualification through licensure and ramp up 

  • Author, review, and/or edit procedures and technical documents to support regulatory filings including standard operating procedures, job aides, and learning documents

  • Promote a culture of visibility and accuracy of the project schedule and update dashboards accordingly to highlight project status to critical milestones


  • Lead and support daily (Tier) meetings to facilitate flow of information up/down through the organization

  • Hold regular team meetings to cascade information and collect team feedback

  • Provide clear consistent communication from shift to shift

  • Escalate issues as needed to ensure the right support/awareness is given to issues as they arise

  • Serve as a Subject Matter Expert (SME) during tours to provide area/process overview information to visitors/auditors upon request

Quality & Safety Compliance

  • Foster strong safety culture on the team through actions, coaching, and prioritization

  • Coach individuals when reporting safety issues and completing corrective/preventative actions

  • Drive culture of compliance through actions, consistent quality-driven decision making, and coaching of the team (e.g. documentation, housekeeping, area 5S, etc.)

  • Participate in safety/regulatory audits (i.e. tours, topic discussion)


  • Coach the team to ensure SAP transaction completion is timely and accurate

  • Manage team staffing and overtime to support customer demand while meeting budget targets

  • Recognize opportunities for cost savings and communicates them for potential project chartering

Education Requirements

  • High School Diploma AND at least Six (6) years in a manufacturing, technical, support, or Military role OR

  • Bachelor's degree in a technical field AND at least Four (4) years in a manufacturing, technical, support, or Military role 

Required Experience and Skills

  • Willingness to work a flexible schedule covering various shifts

  • Demonstrated ability to lead a team (i.e. experience leading directly as a supervisor/coach or indirectly as part of a project or through routine process execution)

  • Ability to manage multiple priorities and coordinate people/resources to meet a production schedule

  • Strategic and effective interpersonal, communication, and problem-solving skills

Preferred Experience and Skills

  • Previous supervisor role

  • Working knowledge of Good Manufacturing Practices (GMP)

  • Electronic manufacturing systems (e.g. PAS-X, SAP, Delta-V, GLIMS etc.)

  • Interacting with regulatory auditors as part of area tours and/or topic discussion

  • Certified Yellow Belt/Green Belt/Black Belt

  • Drug Substance/Product start-up

Our Manufacturing & Supply Division is dedicated to being the most trusted supplier of bio-pharmaceuticals worldwide. Our facilities, along with our external contractors, suppliers, and partners, create a reliable global manufacturing network that's devoted to delivering a high quality, reliable supply to customers and patients on time, every time. 

Who we are …

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for …

Imagine getting up in the morning for a job as important as helping to save and improve lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a diverse group of colleagues who pursue and bring hope to countless people who are battling some of the most challenging diseases of our time. Our team is constantly evolving, so if you are among the intellectually curious, join us—and start making your impact today.


In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

For more information about personal rights under Equal Employment Opportunity, visit:

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Pay Transparency Nondiscrimination

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

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Requisition ID:R136930

Job Requirements

(see job description above)
(Job number: 4052863)
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