NCBiotech Jobs Board ● Connecting North Carolina's life science employers and workforce.

Job: Senior Biostatistician, Institute for Medical Research, Inc., Durham, NC

Employer banner ad -

General Information

Job title:
Senior Biostatistician
Job location:
Durham, NC  27701 United States
Requisition code:
508 Fulton St, IMR - 151
Date posted:
The salary range for this role is $90K- $120K annually. Salary will be commensurate with experience level. IMR offers competitive benefits package including health, dental vision and life insurance. Short and long term disability insurance as well as a retirement plan.
Job category:
Clinical Research
Employment type:
Full time

Job Description

The Institute for Medical Research, an affiliate of the Durham VA Health Care System (DVAHCS) is looking for a Senior Biostatistician to manage statistical projects and perform advanced-level statistical analysis and programming for clinical research studies conducted by the Principal Investigator, Dr. Stephen Freedland, and his associates in his urology research lab. This includes management of projects and junior-level biostatisticians, statistical programming, statistical analysis, quality assurance of data, study planning and feasibility assessments, assistance with grant writing, and presentation of work in reports, manuscripts, posters, and presentations.

The Biostatistician will collaborate closely with a cross-functional project team comprised of physicians, scientists, and research personnel to advise on and execute statistical elements of each project. Studies include prospective observational research, clinical trials, tissue and serum-based studies, and retrospective population studies.

Job Duties:

Collaborate and work effectively with research team members:

Collaborate effectively with programmers, statisticians, investigators, research staff, and external collaborators
Represent the statistical team in project team meetings; make recommendations about study design and execution in relation to statistical analysis
Participate in conference calls, project meetings, weekly meetings with leadership, and other team meetings
Serve as a resource for other statisticians and research staff
Supervise study personnel:

Provide management, support, and training for junior-level biostatisticians
Oversee and assist with employees’ individual research projects, such as by reviewing code and statistical plans, as needed
Meet with other statisticians on a regular basis to provide ongoing support
Effectively manage and execute assignments:

Adhere to standard operating procedures (SOPs) as they apply to documentation and validation of clinical research statistics; provide recommendations for improvement of SOPs over time
Take initiative to complete project-specific responsibilities
Set timelines and deadlines for statistical planning and analyses
Demonstrate ability to multi-task and meet deadlines as appropriate
Build documentation and organizational skills for reproducibility
Statistical analysis planning, generation of results, and interpretation:

Participate in all statistical aspects of a medical research project
Evaluate research studies and recommend statistical procedures to analyze the data
Contribute meaningfully to discussions of analyses and identify next steps for analyses
Perform power calculations for research studies
Write the statistics section of study proposals and grants
Write statistical analysis plans
Develop new statistical methodology as needed for a project
Perform quality assurance reviews of datasets before beginning analysis
Research and apply new statistical methods, as needed
Perform intermediate and advanced statistical analyses, including but not limited to survival analysis (cox modeling, competing risks), linear regression, and generalized linear modeling. Check results for accuracy and consistency
Prepare comprehensive statistical reports to communicate findings with investigators and collaborators
Be able to work on any phase of a manuscript project, from initial meeting with an investigator to final review of a manuscript prior to submission for publication
Prepare statistical components of presentations, abstracts, study protocols, and manuscripts including methods and results sections
Programming and data documentation:

Program analysis datasets using SAS, R, or STATA; combine multiple disparate raw databases and derive analysis variables accurately
Design analysis data set specifications through writing own programming code
Demonstrate good programming practices through proper documentation, commenting, and readability
Perform complex programming using advanced options in SAS procedures and macros, and R functions with increasing efficiency
Produce quality statistical output products including tables, listings, and figures
Perform appropriate and adequate code checks to ensure accuracy of results
The above statements describe the general nature and level of work being performed by individuals assigned to this classification. This is not intended to be an exhaustive list of all responsibilities and duties required of personnel so classified.

Required Skills and Experience:
Requires an organized, task oriented, deadline-sensitive individual with a minimum of a master’s degree in (bio)statistics or a related field and 7 years of relevant experience or a PhD in (bio)statistics or a related field with 2 years of relevant experience. Candidates must have demonstrated statistical programming experience with SAS, R, and STATA. Experience with python or SQL is a plus. Prior experience leading projects with observational, survival, longitudinal, categorical, and generalized linear models is strongly preferred. Candidates should have published work reflecting their collaborative research experience. Experience supervising, leading teams, and managing projects is strongly desired. Writing and programming samples will be requested during the interview process.

Candidates must be able to work diplomatically and professionally with investigators, scientists, and lab personnel. Demonstrated professional initiative, teamwork abilities, strong interpersonal relationship skills, and good decision-making is expected. Excellent written and oral communication skills and experience with Microsoft Windows, Word, and Excel are required for this position. Understanding of HIPAA considerations is preferred.

Applicant must have the ability to work independently in a fast-paced environment, prioritize and manage the workflow of multiple projects. The physical requirements and activities that are required in order to perform the essential functions of the position include, but may not be limited to: must be able to sit for extended periods of time, and must be able to regularly use fingers and hands for computer work, lift up to 5 pounds, and have fluency in the English language.

The prior statements describe the general nature and level of work being performed. This is not intended to be an exhaustive list of all responsibilities and duties required. Employees may be directed to perform job-related tasks other than those specifically presented in this description.

Employees work for the Institute for Medical Research and will have an appointment at the Durham VAHCS. Please visit for information about employee benefits. Employees must undergo a federal background check prior to hiring. We do not sponsor applicants for work visas. We are an equal-opportunity employer.

The salary range for this role is $90K- $120K annually. Salary will be commensurate with experience level.

Participation in the seasonal influenza and Coronavirus Disease 2019 (COVID-19) Vaccination programs are requirements for all Department of Veterans Affairs Health Care Workers Without Compensation (WOC).

Equal Opportunity Employer, including disabled persons and Veterans.

Job Requirements

(see job description above)
(Job number: 4051095)
Do you know someone who would be interested in this job?   Tell them about it.