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Job: Histotechnician / Histotechnologist, In Vivo Pharmacology, StrideBio, Durham, NC

General Information

Job title:
Histotechnician / Histotechnologist, In Vivo Pharmacology
Job location:
Durham, NC  27709 United States
Requisition code:
Date posted:
Job category:
Employment type:
Full time

Job Description

StrideBio is a product-driven, fully integrated gene therapy company focused on creating and developing innovative genetic medicines with life-changing or curative potential for patients with devastating conditions, including monogenic rare disease and beyond.

We leverage our proprietary structure-inspired adeno-associated virus (AAV) vector engineering platform (STRIVE) to create unique and differentiated vectors that improve upon naturally occurring AAV serotypes to overcome current limitations of first-generation gene therapies. Combined with our genetic construct design expertise and in-house manufacturing capabilities, StrideBio is positioned to generate best-in-class genetic medicines that allow more patients to benefit with maximum efficiency, leading to improved treatment outcomes.

Our team is comprised of accomplished leaders and talented, passionate colleagues with a desire to translate innovative science into treatments. Together with our collaborators we are making rapid progress on our mission to bring novel medicines to patients who desperately need them. StrideBio's offices, labs and manufacturing facility are located in the heart of Research Triangle Park, NC, within 10 miles of downtown Durham and Raleigh-Durham International Airport. Please visit to learn more.


The purpose of this position is to support the preclinical team across different programs to accomplish specific goals. You will assist the Sr. Histotechnologist in preparation of tissue specimens for research experiments and be responsible for the maintenance of laboratory equipment and the execution of staining procedures to ensure the utmost quality. You will contribute your expertise in histological and molecular techniques to evaluate tissue samples, quantifying and assessing staining. Your talents will help facilitate rapid progress toward the development of gene therapy. This is an approximate 90% lab-based position in a BSL II material laboratory.


Under general supervision, perform routine and non-routine activities involved in the preparation of slides for microscopic evaluation and analysis.
Based on experience, may perform all phases of tissue preparation including tissue fixation, fresh or in-process specimens (paraffin and frozen), embedding procedures, microtome and cryostat sectioning and mounting of tissues.
Able to train and use of Benchling to register samples that comes into the lab.
Maintain inventory of all tissues processed including electronic file generation (Benchling) to record number of blocks and slides prepared for each study.
Prepare slides for H&E (Hematoxylin & Eosin) staining, Special Stains and immunohistochemistry/immunofluorescent stains for microscopic and image analysis.
Perform coverslipping of stained slides manually or automated.
Ensure proper disposal of chemicals used for histology. Maintain compliance with internal and external regulations for usage of histology chemicals, demonstrating knowledge of quality and safety.
Assist in filing, stocking, and maintaining an adequate inventory of supplies for work area.
Operate and maintain specialized histology equipment and instrumentation according to manufacturer recommendations and procedures.
Perform a variety of routine tasks to support the preclinical team.
Perform other duties as assigned by the Sr. Histotechnologist.
Overall Responsibilities:

70%- hands-on in tissue processing. Staining and image acquisition
20%-electronic documentation, review, and analysis. Maintain equipment and records.
10%-prepare laboratory reagents and verify inventory

Bachelors a/o associate degree in Biology or an equivalent science, and/or appropriate histologic training program.
0-3 years of experience as a Certified Histology Technician/Histotechnologist HT or HTL(ASCPcm) or acquired within the first year of employment.
Knowledge of histology laboratory functions, practices, and procedures.
Strong organizational and communication skills.
Excellent attention to detail, with ability to follow detailed work instructions.
Must be a self-motivated, flexible, and driven professional who can effectively perform in a rapidly changing, small company environment.
Must be able to work independently, but is also a team player with strong collaborative skills.

Experience in a research environment a plus
(H&E) and Special Stains experience.

Ability to move 25 lbs. required
Must be able to perform repetitive motion activities for long periods of time
Must be able to stand for long periods of time

We offer a competitive salary and excellent benefits package including:

Stock Options and Bonus
Medical, Dental, and Vision health insurance
Matching 401k plans (both Pre-tax and Roth Post-tax)
Life/AD&D, Long-term and Short-term disability
Employee Assistance Program
Voluntary: Supplemental Life, Critical Illness, Group Accident, Hospital Indemnity, Identity Theft Protection
Additionally, we provide the following perks:

Relocation Services
Retail Member Discount Programs
Complimentary onsite gym membership
Fully stocked kitchen
Socials, happy hours, and other events throughout the year (currently "virtual")

For more information, or to apply now, you must go to the website below. Please DO NOT email your resume to us as we only accept applications through our website.

Job Requirements

(see job description above)
(Job number: 3981940)
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