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Job: Research Associate, Therapeutic Discovery, StrideBio, Durham, NC

General Information

Job title:
Research Associate, Therapeutic Discovery
Job location:
Durham, NC  27709 United States
Requisition code:
Date posted:
Job category:
Research and Development
Employment type:
Full time

Job Description

StrideBio is a product-driven, fully integrated gene therapy company focused on creating and developing innovative genetic medicines with life-changing or curative potential for patients with devastating conditions, including monogenic rare disease and beyond.

We leverage our proprietary structure-inspired adeno-associated virus (AAV) vector engineering platform (STRIVE) to create unique and differentiated vectors that improve upon naturally occurring AAV serotypes to overcome current limitations of first-generation gene therapies. Combined with our genetic construct design expertise and in-house manufacturing capabilities, StrideBio is positioned to generate best-in-class genetic medicines that allow more patients to benefit with maximum efficiency, leading to improved treatment outcomes.

Our team is comprised of accomplished leaders and talented, passionate colleagues with a desire to translate innovative science into treatments. Together with our collaborators we are making rapid progress on our mission to bring novel medicines to patients who desperately need them. StrideBio's offices, labs and manufacturing facility are located in the heart of Research Triangle Park, NC, within 10 miles of downtown Durham and Raleigh-Durham International Airport. Please visit to learn more.


The purpose of this position is to assist preclinical development activities in the application of novel recombinant adeno-associated virus (rAAV) vectors. We seek a motivated and curious individual at the Research Associate level to join the Therapeutic Discovery team, which is part of our Preclinical group. You will be expected to have strong technical and laboratory documentation skills. Experience with Neuroscience is desired.

You will execute experiments and develop assays for our Rett syndrome project. You will perform and design experiments alongside the scientific lead in order to develop, test, and validate AAV cassettes in vitro using different cell models of Rett Syndrome. This is an approximate 80% lab-based position in a BSL II material laboratory.


Maintain multiple cell types in culture for the purposes of in vitro testing including primary cells (training provided)
Perform molecular biology (DNA, RNA, protein isolation from tissues and cells), cellular biology (transductions, transfections, IHC, IF), and analytical testing (i.e. ELISA, Western blot, qPCR) for routine as required
Maintain accurate and up-to-date record of laboratory activities via electronic documentation
Assist with technical writing of procedures and protocols
Maintain and update knowledge of instrumentation and laboratory needs
Execute laboratory work plan/schedule developed with input from supervisor or senior team members
Understand and interpret experiments that contribute to project goals
Conduct troubleshooting analysis
Perform other essential tasks/responsibilities as assigned


BS with a minimum of 2 years/ MS with 0 years of experience in virology, immunology, molecular biology, cell biology or other relevant scientific area. Level is commensurate with experience
Experience with molecular biology is required.
Exemplary organizational skills, along with notebook maintenance and writing skills
Must be a self-motivated, flexible, and driven professional who can effectively perform in a rapidly changing, small company environment
Must be able to work independently, but is also a team player with strong collaborative skills


Cell culture expertise
Cell-based assay development
Familiarity with microscopy
Neuroscience experience


We offer a competitive salary and excellent benefits package including:

Stock Options and Bonus
Medical, Dental, and Vision health insurance
Matching 401k plans (both Pre-tax and Roth Post-tax)
Life/AD&D, Long-term and Short-term disability
Employee Assistance Program
Voluntary: Supplemental Life, Critical Illness, Group Accident, Hospital Indemnity, Identity Theft Protection

Additionally, we provide the following perks:

Relocation Services
Retail Member Discount Programs
Complimentary onsite gym membership
Fully stocked kitchen
Socials, happy hours, and other events throughout the year (currently "virtual")

For more information, or to apply now, you must go to the website below. Please DO NOT email your resume to us as we only accept applications through our website.

Job Requirements

(see job description above)
(Job number: 3948465)
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