Job: Scientist/Senior Scientist, Quality Control, StrideBio, Durham, NC
Scientist/Senior Scientist, Quality Control
Durham, NC 27709 United States
Manufacturing and Production
StrideBio is a product-driven, fully integrated gene therapy company focused on creating and developing innovative genetic medicines with life-changing or curative potential for patients with devastating conditions, including monogenic rare disease and beyond.
We leverage our proprietary structure-inspired adeno-associated virus (AAV) vector engineering platform (STRIVE) to create unique and differentiated vectors that improve upon naturally occurring AAV serotypes to overcome current limitations of first-generation gene therapies. Combined with our genetic construct design expertise and in-house manufacturing capabilities, StrideBio is positioned to generate best-in-class genetic medicines that allow more patients to benefit with maximum efficiency, leading to improved treatment outcomes.
Our team is comprised of accomplished leaders and talented, passionate colleagues with a desire to translate innovative science into treatments. Together with our collaborators we are making rapid progress on our mission to bring novel medicines to patients who desperately need them. StrideBio's offices, labs and manufacturing facility are located in the heart of Research Triangle Park, NC, within 10 miles of downtown Durham and Raleigh-Durham International Airport. Please visit www.stridebio.com to learn more.
You will play a key role in the development of cell-based assays to support process development and manufacturing of recombinant adeno-associated vectors. You will bring your talents of developing assays to our programs with implementation and maintenance of assay performance as well as strategies to address OOT results. Your activities will support manufacturing, provide scientific expertise, and prepare reports. Essential to this role is a strong knowledge base, broad expertise, and the ability to lead and mentor scientific staff and collaborate with cross functional team members. Your passion for working in the lab will be fully utilized.
Perform cell-based assays and other analytical assays to support process development and manufacturing processes.
Perform data analysis, track data trends, and may write reports as needed.
Coordinate timely testing of materials to support preclinical and manufacturing.
Perform numerous tests as needed including ELISAs, qPCR, ddPCR, primer/probe design, infectivity assays, and potency assays.
Communicate scientific content via presentations to internal audiences.
Prepare and/or review Test Procedures, SOPs, and Protocols, as necessary.
KNOWLEDGE AND SKILLS:
Ph.D. degree in Cell Biology, Biological Sciences, or other related field with 2+ years of experience, an M.S. degree with 8+ years, or a B.S. degree with 10+ years of laboratory experience from the life sciences industry.
Significant experience working with cells/cell culture, cell-based and potency assays is required.
Experience working with biologics preferred.
Experience and adept at using aseptic sterile technique.
Understanding of analytical development and testing.
Experience with other analytical assays (ex. ELISA or qPCR) and flow cytometry is highly preferred.
Experience working in a GLP, GMP, or CLIA laboratory environment preferred, including familiarity with FDA, ICH and GMP guidelines.
Must have outstanding attention to detail, along with strong organizational and documentation skills.
Must have demonstrated experience effectively managing multiple projects and staff and troubleshooting experiments, but also an analytical problem-solver who thrives on solving scientific challenges.
SoftMax experience is highly preferred, with GraphPad Prism experience a plus.
Must be a self-motivated and driven professional who can effectively perform in a rapidly changing, small company environment.
Must be able to work independently but is also a team player with strong collaborative skills.
COMPENSATION & BENEFITS:
We offer a competitive salary and excellent benefits including stock options, PTO, Medical, Dental, Vision, 401k match, disability and life insurance. Additionally, we provide the following perks:
Complimentary onsite gym membership
Fully stocked kitchen
Socials, happy hours and other events throughout the year
Access to an onsite full-service restaurant (Coming Soon!)
For more information, or to apply now, you must go to the website below. Please DO NOT email your resume to us as we only accept applications through our website.
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