Job: Scientist, Biostatistics/Bioinformatics, Precision BioSciences, Durham, NC
The Scientist, Biostatistics/Bioinformatics works within the BioAnalytical Team at Precision Biosciences focused on the development of genome-edited allogeneic CAR-T therapeutics. The incumbent will play a lead role in the identification and implementation of existing and/or novel algorithms, analytical techniques and computational procedures to mine, clean, and interpret a wide variety of data derived from genomic, proteomic, metabolomic, and cellular phenotypic methods. This team member will be a part of our broader CMC organization which aims to drive technical excellence for the successful development of Precision Biosciences’ Cell and Gene Therapy Products, including allogeneic CAR-T cells, AAV viral vectors, and Lipid Nanoparticle-Encapsulated mRNA spanning a broad range of indications in immuno-oncology, infectious disease, and rare genetic disease.
Essential Duties and Responsibilities
Identify and utilize appropriate feature selection and dimensionality reduction techniques to support data analysis
Identify and implement appropriate computational pipelines using existing tools to assist research groups in streamlining data analysis
Identify appropriate checks and analytics to ensure accurate and consistent data analysis
Assist with building and overseeing internal databases
Expertise in supervised and unsupervised machine learning (including Deep Learning) applied to different datasets, feature selection and dimensionality reduction techniques
Experience with RNAseq and/or flow cytometry data processing and analysis
Knowledge of fundamental concepts in immunology and genetics
Strong skills in statistical analysis
Ability to work as part of a team collaboratively using inquisitiveness and active listening
Excellent communication skills with an ability to present data and analysis to experts and non-experts alike
Experience with data visualization
Strong experience with R (Bioconductor, etc.), Python (Tensorflow, Scikit-learn), MATLAB®
Command-line, bash experience
Database concepts (design and use)
Visualization tools (e.g., Tableau)
Successful candidate should have an advanced degree (M.S. and/or Ph.D.) in computer science, statistics, computational biology or similar with at least 2 years of relevant experience or equivalent contributions
This role is envisioned to initially be an individual contributor, but may eventually supervise a small team of 2-3 direct reports
This position requires little to no travel.
This position is located at the main headquarters in Durham, NC, and is required to physically be and work in the office, in order to be most effective, and at managers discretion.
Precision BioSciences is dedicated to improving life through its proprietary genome editing platform, “ARCUS.” Precision BioSciences leverages ARCUS in the development of its product candidates which are designed to treat human diseases and create healthy and sustainable food and agriculture solutions. Precision BioSciences is actively developing product candidates in three innovative areas: allogeneic CAR T immunotherapy, in vivo gene correction, and food.
Precision BioSciences provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, disability, genetic information, marital status, amnesty, or status as a covered veteran in accordance with applicable federal, state and local laws. Precision BioSciences complies with applicable state and local laws governing non-discrimination in employment in every location in which the company has facilities. This policy applies to all terms and conditions of employment, including, but not limited to, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.