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Job: Senior Scientist Functional Genomics, Element Genomics, Inc., Durham, NC

General Information

Job title:
Senior Scientist Functional Genomics
Job location:
Durham, NC  27701 United States
Requisition code:
Date posted:
Job category:
Research and Development
Employment type:
Full time

Job Description

This is a lab position within the functional genomics group at Element Genomics, a wholly owned subsidiary of UCB Biosciences. The role contributes at an in vitro technical level to design studies, produce and interpret data and contribute to current and future drug discovery projects. Skills should include molecular and cell biology knowledge together with previous experience of range of in vitro based technology capabilities and screening approaches.

Primary responsibilities :
• Design and execution of functional genomics assays/screens to identify and validate novel targets including assessment of relevant biology in screening models and validation of hits
• Provide strategic guidance to maximize best applications of functional genomics technology and how it can be evolved to better address UCB needs in the future, including capturing learnings on both projects and functional genomics platform
• Drive projects locally with clear scientific direction and focus on critical path experiments, including providing scientific supervision as needed to more junior scientists and engaging with the broader team
• Provide scientific insight and guidance in projects/platforms, including strong scientific thinking and hypothesis development, in collaboration with cross-functional teams at UCB (medicinal chemists, cell biologists, disease area exerts, antibody engineers, etc)
• Time split between wet lab (experiments, data analysis, planning, ordering) and office responsibilities (meetings, presentations, keeping up with the literature)

Job Requirements

Education and experience:
• PhD in applicable field with record of scientific achievement as evidenced by publications, presentations, or patents
• 3+ years of experience in application of functional genomics
• Experience of applying cellular and biochemical techniques for target identification, validation, genetic screening and evaluating the mechanism of action of novel molecular entities
• Demonstrated experience in a matrixed drug discovery environment including working globally
• Experience in molecular biology approaches and advanced cell biology techniques (flow cytometry, gene and protein analysis, PCR, cloning, lentiviral library prep)
• Experience in assay development and high content imaging preferred
• Excellent communicator, with demonstrated ability to work across disciplines
• Ability to work independently, manage priorities, and engage in a multidisciplinary environment
(Job number: 3847177)
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