Research and Development
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Job: Postdoctoral Fellow in synthetic biology and cell therapy, Hingtgen Lab at UNC Chapel Hill, Chapel Hill, NC
Postdoctoral Fellow in synthetic biology and cell therapy
Chapel Hill, NC 27516 United States
Research and Development
The Division of Pharmacoengineering and Molecular Pharmaceutices (DPMP) seeks to create new methods of targeted delivery to optimize therapeutic efficacy of drugs and vaccines. This is accomplished by the integration of drug-delivery science, nanotechnology, and pharmacoengineering, an emerging discipline that integrates engineering methods with pharmaceutical sciences. The division works closely with other divisions within the UNC Eshelman School of Pharmacy, as well as other divisions across campus, including numerous researchers from the Lineberger Comprehensive Cancer Center. DPMP researchers have generated more than $8.5M in annual support from the NIH and NSF. This includes the NIH-funded Center for Nanotechnology in Drug Delivery that brings together scientists to create nano-scale pharmaceutical innovations for therapeutic and diagnostic purposes.
Building on a new partnership partnership between the J. Craig Venter Institute and The Hingtgen Lab, we seek to fill a post-doctoral position. The work will focus on an exciting new project aimed at creating the next-generation cell therapy by working at the interface of synthetic biology and cell therapy. Foundations of this work include:
1. Sci Transl Med. 2017 Feb 1;9(375). pii: eaah6510
2. Nat Commun. 2016 Feb 2;7:10593
Ph.D. degree in biomechanical engineering, drug delivery, or cellular therapies.
Preference will be given to candidates with experience in:
- The development and testing of cell therapies, including CAR-T, dendritic, mesenchymal, etc.
- Culturing and manipulation of neural stem cells or other stem cells types.
- The generation and use of tumoricidal neural stem cells for treatment of cancer.
- Culture and delivery of stem cells on various bio-degradable scaffold technologies.
- The development and use of scaffold-based drug delivery systems for cancer therapy.
- The use of murine models of cancer.
- Self-motivated, high enthusiasm, independent and creative thinker, and passion to work on innovative projects.
- A strong publication record, effective communication skills, and good team spirit.
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North Carolina Biotechnology Center