Job: Postdoctoral Associates, Duke Human Vaccine Institute, Durham, NC
The Duke Human Vaccine Institute (DHVI), an international leader in the fight against major infectious diseases, is currently recruiting for Postdoctoral Associates to join our research team. The Duke Human Vaccine Institute is an interdisciplinary, interdepartmental institute dedicated to the study of basic and translational science required to understand host-pathogen interactions that can be translated to vaccines against human diseases. Directed by Dr. Barton Haynes, we are a team of highly interactive investigators that have expertise in immunology, molecular biology, virology, microbiology, computational biology, and vaccine science. We are seeking highly motivated recent PhD graduates who are interested in Immunology, Molecular Biology, Biochemistry, Biomedical Engineering, Computational Biology, Virology or related scientific field to play an integral role in the following projects.
• A successful HIV-1 vaccine will require immunogens that induce protective immune responses. One key goal of HIV-1 vaccine development is the induction of broadly neutralizing antibodies (bnAbs). This project will help develop strategies to design immunogens to select B cell lineage antibodies that can develop into bnAbs of interest. These strategies involve modifications of tolerance checkpoints in addition to iterative immunogen design. (Dr. Barton Haynes)
• The Global Health Vaccine Accelerator Platform Antibody Dynamics team aims to evaluate the biophysical properties and antiviral function of antibodies induced in response to vaccination against malaria and other pathogens, with the goal of identifying correlates of protection and informing vaccine design. Experience in immunoassays, functional assays, and biochemistry is preferred. (Dr. Georgia Tomaras)
• This project focuses on the assessment of immune-based strategies for prevention of maternal and pediatric HIV/AIDS and treatment of neonatal infections, including Cytomegalovirus, Zika Virus, and HIV-1. Humoral and cellular immune assays will be utilized to define protective maternal and infant immune responses and virus reservoirs at the maternal-fetal interface in both human clinical trials and nonhuman primate models. (Drs. Sallie Permar and Genevieve Fouda)
The DHVI has a dynamic mentoring program, directed by Dr. Georgia Tomaras, and our postdoctoral associates work in concert with Duke faculty and staff in an invigorating research training environment. One of our primary scientific missions is to support and train early stage investigators to be the next generation of scientific leaders equipped to identify and implement solutions for improving human health worldwide.
DHVI functions as a vaccine development biotechnology enterprise, embedded within a top university. As a trainee within our mentoring program, you will interact with highly innovative and collaborative investigators and have the opportunity to master state of the art technologies. We are committed to providing an outstanding training environment and research experiences that will enhance your career and provide you an avenue to incorporate your education, expertise, initiative and dedication to the success of the studies. This is an opportunity to become part of a winning team that is working to discover novel ways to prevent infectious diseases.