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Job: Postdoctoral Associate, CHDM, Durham, NC
Durham, NC 27701 United States
Research and Development
Job Description: There are immediate Postdoctoral Associate training opportunities available within the Center for Human Disease Modeling (CHDM). Dr. Nicholas Katsanis (Director) along with faculty members Erica Davis, I-Chun Tsai and Weibin Zhou are inviting applications from candidates who will be considered for a wide range of interdisciplinary projects funded by NIH. Our Center offers a unique, project-based atmosphere that is highly collaborative in a shared-resource setting. The ideal candidates will be accomplished, highly motivated, and creative scientists with interests in at least one of the three following areas: 1) understanding the architecture of human genetic disease; 2) investigating the mechanisms underlying disease processes and pathomechanism; and 3) identification of novel therapeutic paradigms for inherited disorders. Candidates will have the opportunity to work with unique patient cohorts; cell-based, zebrafish and/or mouse models; and cutting-edge molecular and imaging technologies in a state-of-the-art facility.
Research topics can be chosen based on the interests and background of the individual candidate. Positions will be offered with a renewable one-year appointment with the expectation of at least a three-year term. Potential projects include, but are not limited to the following research themes:
• Genetic and functional investigation of rare structural birth defects
• Functional study of novel candidate genes that cause gonadotropin releasing hormone (GnRH) abnormalities
• Cis complementation and phenotype modifier phenomena in ciliopathies
• Dissection of copy number variants in neuroanatomical traits
• Mechanistic study of inherited kidney disorders affecting renal structure or function
• Investigation of novel genes underlying treatment-resistant schizophrenia
• Therapeutic target discovery in rare pediatric disorders
Candidates will be mentored by at least one CHDM faculty member.
Position Requirements: Ideal candidates will have a recent PhD in the life sciences (less than 2 years of postdoctoral experience is strongly preferred), or who anticipate completion of their degree prior to starting the position. Previous experience in genetics; cell, molecular, or computational biology; botany; zoology or other directly related scientific fields are desirable but not required. Qualifying competencies include strong verbal and written English skills, excellent organizational skills, self-motivation, and creativity.
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North Carolina Biotechnology Center