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Cell Based Assay Development Associate Investigator/Investigator
Research Triangle Park, NC 27709 United States
ScitoVation is dedicated to understanding how chemical compounds affect human health and developing non-animal based approaches to human safety assessment. We help our clients develop safer and more effective pharmaceuticals, food ingredients, agricultural chemicals, commodity chemicals and consumer products through the development of fit-for-purpose, human cell-based in vitro assays and computational models.
We are seeking a cellular/molecular biologist to lead research in the design, development, and validation of cell-based assays for the evaluation of toxicological endpoints relevant to safety science. The candidate should have a combination of experience in general molecular biology techniques, cell culture methods, application of simple 2D or 3D cell models or more complex organotypic systems, and high-throughput assays.
The successful candidate for this position has a doctoral degree in cell biology, genetics, molecular toxicology or a related field with significant background in cell and molecular biology. A demonstrated track record of managing multiple projects, supervising technical staff, and writing proposals for external research sponsorship is strongly preferred. Expertise in in vitro alternatives for the following toxicity endpoints are of particular interest: primary hepatocyte culture and liver toxicity, developmental toxicity, endocrine disruption (thyroid, androgen), cardiac, brain and kidney toxicity.
•A PhD in molecular biology, cell biology, pharmacology, molecular toxicology, or similar disciplines is required
•At least 2 years of work experience post-graduate studies
•Experience in phenotypic assay development or optimization for medium or high-throughput screening
•Experience with advanced techniques such as organotypic or 3D cell culture model systems, high content imaging and/or flow cytometry for high throughput assays is preferred, but not essential
•Independently managed multiple projects and personnel
•Self-driven individual with strong organizational skills
•Excellent communication skills - both verbal and written
•Ability to work in a team environment and guide research to support overall company goals
North Carolina Biotechnology Center